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Online Gamers Crack Aids Enzyme Puzzle

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"Many,,,,of,,,,the,,,,people,,,,playing,,,,the,,,,game,,,,are,,,,known,,,,only,,,,by,,,,their,,,,user,,,,name,,,,,even,,,,within,,,,a,,,,teamA,,,bored,,,mind,,,given,,,something,,,interesting,,,,then,,,multiplied,,,by,,,10000,,,is,,,ALOT,,,of,,,processing,,,power,,Shepard1707,,,Sep,,19,,,2011,,#9,,firefossil,,I,,have,,charts"The,,team,,members,,come,,from,,a,,wide,,range,,of,,backgrounds,,,chiefly,,scientific,,or,,IT,,[information,,technology],,,although,,our,,best,,player,,is,,from,,neitherlolz,,,just,,,kidding,,,hmm,,,i,,,wonder,,,what,,,can,,,they,,,do,,,with,,,all,,,of,,,this,,,o.oClick,,,to,,,expand"After,,,,this,,,,discovery,,,,,young,,,,people,,,,might,,,,not,,,,mind,,,,doing,,,,their,,,,science,,,,homework,",,,,she,,,,quippedIt,,,,doesn't,,,,matter,,,,,what,,,,the,,,,Experts,,,,couldn't,,,,do,,,,in,,,,10,,,,years,,,,,a,,,,bunch,,,,of,,,,gamers,,,,did,,,,in,,,,LESS,,,,then,,,,10,,,,daysCreate,,account,,now!,,Home,,News,,Sport,,Business,,World,,Politics,,Comment,,Property,,Entertainment,,Lifestyle,,Travel,,Cars,,Tech,,Video,,All,,News,,NSW,,News,,National,,Environment,,Health,,Education,,Investigations,,Good,,Weekend,,Galleries,,Clique,,Photos,,Victoria,,News,,Queensland,,ACT,,News,,WA,,News,,Sport,,NRL,,Union,,AFL,,Football,,Cricket,,Racing,,Motorsport,,Basketball,,Netball,,Cycling,,Tennis,,Scores,,Golf,,US,,Sports,,Athletics,,Swimming,,Boxing,,Sailing,,News,,Markets,,Quotes,,Workplace,,Consumer,,Property,,Innovation,,Retail,,Economy,,CBD,,Money,,Small,,Business,,Politics,,Politics,,Political,,Opinion,,Video,,Cartoons,,The,,Pulse,,Federal,,Election,,2016,,Your,,Vote,,Electorate,,Map,,Comment,,Letters,,Editorials,,Column,,8,,Obituaries,,Peter,,Hartcher,,Ross,,Gittins,,Jessica,,Irvine,,Blunt,,Instrument,,Satire,,Entertainment,,Movies,,TV,,&,,Radio,,Music,,Books,,Art,,Stage,,What's,,On,,in,,Sydney,,Video,,Shop,,Art,,Lifestyle,,News,,&,,Views,,Life,,&,,Relationships,,Health,,&,,Wellbeing,,Beauty,,Fashion,,Horoscopes,,Celebrity,,Home,,The,,Optimist,,Tech,,News,,Security,,Web,,Culture,,Innovation,,Sci-Tech,,Gadgets,,Games,,eSports,,Smartphone,,Apps,,Mobiles,,Video,,News,,Sport,,Business,,Entertainment,,Lifestyle,,Travel,,Property,,Cars,,Food,,Exec,,Style,,Parenting,,Search,,Site,,Privacy,,,Policy,,,Disclaimer:,,,You,,,are,,,being,,,added,,,to,,,a,,,mailing,,,list,,,which,,,you,,,can,,,unsubscribe,,,at,,,any,,,time

 

lolz,,just,,kidding,,hmm,,i,,wonder,,what,,can,,they,,do,,with,,all,,of,,this,,o.o,,,,CrzBioHazard,,,Sep,,19,,,2011,,RadioHavana,,Noob,,Joined:,,Dec,,1,,,2009,,Messages:,,701,,Date,,Posted:,,Sep,,19,,,2011,,#7,,CrzBioHazard,,said:,,What,,the!?!?!,,These,,aren't,,gamersFortunately,,,the,,challenge,,fit,,the,,current,,capabilities,,of,,the,,Foldit,,game,,,so,,Khatib,,and,,his,,colleagues,,put,,the,,puzzle,,out,,there,,for,,Foldit's,,teams,,to,,work,,onCut,,,it,,,anyway,,,you,,,like,,,it,,,,call,,,it,,,whatever,,,you,,,like,,,it,,,,what,,,you,,,said,,,above,,,is,,,correct,,,more,,,or,,,lessTo,,the,,astonishment,,of,,the,,scientists,,,the,,gamers,,produced,,an,,accurate,,model,,of,,the,,enzyme,,in,,just,,three,,weeks,,juegosmajicos,,,Sep,,19,,,2011,,bryan12112,,Star,,Joined:,,Apr,,13,,,2001,,Messages:,,48,612,,Date,,Posted:,,Sep,,19,,,2011,,#5,,CoolThe,,Contenders,,are,,spread,,out,,between,,Canada,,,USA,,,UK,,,Europe,,and,,New,,Zealand,,,so,,this,,is,,essentialThere,,is,,both,,global,,chat,,,which,,everyone,,can,,access,,,and,,individual,,group,,chat,,,which,,allows,,team,,members,,to,,talk,,easily,,to,,one,,another"I,,would,,be,,grateful,,if,,you,,could,,refer,,to,,me,,as,,'mimi',,rather,,than,,using,,my,,full,,name.",,Update,,for,,12:45,,p.mBoards,,Recent,,Activity,,Search,,Boards,,Search,,titles,,only,,Posted,,by,,Member:,,Separate,,names,,with,,a,,comma

 

Newer,,,,Than:,,,,Search,,,,this,,,,thread,,,,only,,,,Search,,,,this,,,,forum,,,,only,,,,Display,,,,results,,,,as,,,,threads,,,,More"Each,,,,player,,,,can,,,,work,,,,on,,,,a,,,,solo,,,,solution,,,,to,,,,a,,,,puzzle,,,,,but,,,,we,,,,can,,,,also,,,,exchange,,,,solutions,,,,between,,,,the,,,,team,,,,and,,,,add,,,,our,,,,own,,,,improvements,,,,to,,,,achieve,,,,a,,,,better,,,,resultA,,body,,of,,knowledge,,has,,been,,built,,up,,in,,the,,Wiki,,by,,contributions,,from,,players,,,and,,ideas,,are,,constantly,,fed,,back,,to,,the,,game,,designersTheir,,,,target,,,,was,,,,a,,,,monomeric,,,,protease,,,,enzyme,,,,,a,,,,cutting,,,,agent,,,,in,,,,the,,,,complex,,,,molecular,,,,tailoring,,,,of,,,,retroviruses,,,,,a,,,,family,,,,that,,,,includes,,,,HIV"Can,,,the,,,Foldit,,,players,,,really,,,solve,,,it?",,,They,,,couldHe's,,,not,,,alone,,,in,,,that,,,hope,,Mith,,,Sep,,19,,,2011,,#21,,Gil,,Hamilton,,Burajin,,Desutoroiyaa!,,Piece,,of,,Mind,,said:,,↑,,Heh,,,they,,built,,a,,multi,,core,,peopleputer,,[edit],,You,,know,,what,,,if,,they,,could,,commercialise,,this,,you,,could,,find,,endless,,employment,,for,,those,,millions,,of,,long,,term,,jobless,,and,,low,,skilled,,workers.Click,,to,,expandInternational,,Sites,,World,,Africa,,Adria,,Adria,,(Slovenia),,AU,,Benelux,,Brazil,,CA,,Denmark,,Finland,,France,,Germany,,Greece,,Hungary,,India,,IE,,Israel,,Italy,,Japan,,Latin,,America,,Middle,,East,,(Arabic),,Middle,,East,,(English),,Norway,,Pakistan,,Poland,,Portugal,,Romania,,Russia,,Southeast,,Asia,,Spain,,Sweden,,Turkey,,UK,,US,,Full,,Site,,Accessibility,,Contact,,Us,,Privacy,,Policy,,Terms,,of,,Use,,AdChoices,,Copyright,,1996-2017,,,Ziff,,Davis,,,LLCDismiss,,Notice,,Buy,,our,,stuff,,,go,,here,,to,,find,,out,,more:,,Dismiss,,Notice,,Contest,,-,,Shipyard,,Fleet,,Buy,,Our,,Stuff,,

 

ET,,Sept12-Apr-2017,,,,,,,,03:43,,,,AM,,,,The,,,,strategy,,,,has,,,,been,,,,compared,,,,to,,,,designing,,,,a,,,,key,,,,to,,,,fit,,,,one,,,,of,,,,Mother,,,,Nature's,,,,locks,,,Cloak&Dagger,,,,Sep,,,19,,,,2011,,,#2,,,Lerticus,,,,,,Senile,,,Old,,,Coot,,,,,,Not,,,unexpected,,,after,,,that,,,whole,,,unlocking,,,the,,,ninth,,,chevron,,,thing,,,,Gil,,,,Hamilton,,,,,Sep,,,,19,,,,,2011,,,,#24,,,,SapphireFox,,,,Fuzzy,,,,Fuzzball,,,,of,,,,DOOM!,,,,Super,,,,Awesome,,,,Happy,,,,Fun,,,,Time,,,,Link,,,,to,,,,Article,,,,Online,,,,gamers,,,,have,,,,achieved,,,,a,,,,feat,,,,beyond,,,,the,,,,realm,,,,of,,,,Second,,,,Life,,,,or,,,,Dungeons,,,,and,,,,Dragons:,,,,they,,,,have,,,,deciphered,,,,the,,,,structure,,,,of,,,,an,,,,enzyme,,,,of,,,,an,,,,AIDS-like,,,,virus,,,,that,,,,had,,,,thwarted,,,,scientists,,,,for,,,,a,,,,decadeBut,,,,players,,,,belonging,,,,to,,,,the,,,,Foldit,,,,Contenders,,,,Group,,,,worked,,,,as,,,,a,,,,tag,,,,team,,,,to,,,,come,,,,up,,,,with,,,,an,,,,incredibly,,,,elegant,,,,,low-energy,,,,model,,,,for,,,,the,,,,monkey-virus,,,,enzymeCracking,,the,,enzyme,,provides,,new,,insights,,for,,the,,design,,of,,antiretroviral,,drugs,,,says,,the,,study,,,referring,,to,,the,,lifeline,,medication,,against,,the,,human,,immunodeficiency,,virus,,(HIV)To,,,,design,,,,the,,,,right,,,,chemical,,,,key,,,,,you,,,,have,,,,to,,,,figure,,,,out,,,,the,,,,most,,,,efficient,,,,,llowest-energy,,,,configuration,,,,for,,,,the,,,,molecule,,,,,,,,the,,,,one,,,,that,,,,Mother,,,,Nature,,,,herself,,,,came,,,,up,,,,withPharmacologists,,,,though,,,,need,,,a,,,3-D,,,picture,,,that,,,unfolds,,,the,,,molecule,,,and,,,rotates,,,it,,,in,,,order,,,to,,,reveal,,,potential,,,targets,,,for,,,drugs

 

Khatib,,,is,,,the,,,lead,,,author,,,of,,,a,,,research,,,paper,,,on,,,the,,,project,,,,published,,,today,,,by,,,Nature,,,Structural,,,&,,,Molecular,,,BiologyIt,,is,,believed,,to,,be,,the,,first,,time,,that,,gamers,,have,,resolved,,a,,long-standing,,scientific,,problemSkip,,,to,,,footerOne,,,,of,,,,Foldits,,,,creators,,,,,Seth,,,,Cooper,,,,,explained,,,,why,,,,gamers,,,,had,,,,succeeded,,,,where,,,,computers,,,,had,,,,failed"This,,,,was,,,,one,,,,of,,,,the,,,,cases,,,,where,,,,his,,,,method,,,,wasn't,,,,able,,,,to,,,,solve,,,,it,",,,,Khatib,,,,saidThat's,,,,where,,,,Foldit,,,,plays,,,,a,,,,roleDeveloped,,,in,,,2008,,,by,,,the,,,University,,,of,,,Washington,,,,Foldit,,,is,,,a,,,fun-for-purpose,,,video,,,game,,,in,,,which,,,gamers,,,,divided,,,into,,,competing,,,groups,,,,compete,,,to,,,unfold,,,chains,,,of,,,amino,,,acids,,,,,,the,,,building,,,blocks,,,of,,,proteins,,,,,,using,,,a,,,set,,,of,,,online,,,toolsThe,,,strategy,,,has,,,been,,,compared,,,to,,,designing,,,a,,,key,,,to,,,fit,,,one,,,of,,,Mother,,,Nature's,,,locksThey,,,tried,,,THIS,,,,and,,,got,,,shown,,,by,,,the,,,gamersThe,,exploit,,is,,published,,on,,Sunday,,in,,the,,journal,,Nature,,Structural,,&,,Molecular,,Biology,,,where,,,,exceptionally,,in,,scientific,,publishing,,,,both,,gamers,,and,,researchers,,are,,honoured,,as,,co-authors

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